CAS 1435-48-9 · 2,4-Dichloro Fluoro Benzene

2,4-Dichloro Fluoro Benzene: direct from source to Europe

2,4-Dichloro Fluoro Benzene (CAS 1435-48-9) is a chloro-fluoro aromatic best known as the starting material for 2,4-dichloro-5-fluoroacetophenone, a central intermediate in fluoroquinolone antibiotic manufacture. Supplied as a liquid with a batch-specific COA.

  • COA, SDS & TDS with every batch
  • REACH status confirmed before quote
  • Samples available for qualification
Purityup to 99.5%+GC purity, premium grade
Lead time3 – 6 weeksOrigin to European port
FormLiquid200 litre drums to bulk
Response1 business dayQuotation after receiving your spec
Product identification

2,4-Dichloro Fluoro Benzene: names, synonyms and identifiers

Buyers search for this material under several names. Whichever one appears on your specification, purchase order or REACH dossier, it is the same compound: 2,4-Dichloro Fluoro Benzene, CAS 1435-48-9.

  • Confirmed CAS number on every COA
  • Premium grade with GC purity 99.5%+ available
  • TDS and SDS supplied with every shipment
Common name
2,4-Dichloro Fluoro Benzene
Synonyms
2,4-Dichlorofluorobenzene · 1,3-Dichloro-4-fluorobenzene · 2,4-DCFB
CAS number
1435-48-9
Formula / MW
C6H3Cl2F  /  164.99 g/mol
Chemical family
Chlorofluorobenzene
HS code
2903 (halogenated derivatives of hydrocarbons). Confirm the full code with your broker.

⚠ Not the same as 2,6-dichlorofluorobenzene (2268-05-5) or 3,4-dichlorofluorobenzene. Always match CAS 1435-48-9.

Technical data

2,4-Dichloro Fluoro Benzene physical and chemical properties

Key parameters for process engineering, safety planning and storage design. Values are typical; always verify against the current TDS for your lot.

Appearance
Colourless to pale yellow liquid
Colourless to pale yellow liquid
Melting point
As per TDS
Typical value
Boiling point
As per TDS
Supplied with each order
Molecular weight
164.99
g/mol
Molecular formula
C6H3Cl2F
Chlorofluorobenzene
Solubility
Low in water
Soluble in common organic solvents
Physical form
Liquid
At room temperature
Storage
Cool & dry
Closed container, away from light
Quality & specification

2,4-Dichloro Fluoro Benzene grade specifications: standard vs premium

Two grades are offered so your process chemist or quality team can pick what suits downstream requirements. COA parameters are confirmed before every shipment.

Parameter
Standard grade
Premium grade
Test method / note
GC purity
≥ 99.0%
≥ 99.5%
GC area %
Water content (KF)
≤ 0.1%
≤ 0.05%
Karl Fischer titration
Total impurities
≤ 0.9%
≤ 0.5%
By GC; individual limits on request
Isomer identity
Confirmed
Confirmed
GC or GC-MS
Appearance
Colourless to pale yellow liquid
Colourless to pale yellow liquid
Visual check

All values are specification limits, not guaranteed minima. Actual COA figures for your lot are provided before dispatch. Non-standard specifications are available on enquiry.

Applications

Where 2,4-Dichloro Fluoro Benzene is used

Typical end uses and synthesis routes for European manufacturers, toll processors and laboratories.

Fluoroquinolone antibiotics

Acylation gives 2,4-dichloro-5-fluoroacetophenone, an intermediate to ciprofloxacin-type APIs.

Pharmaceutical intermediates

Halogenated aryl fragment for other API routes.

Agrochemicals

Building block for fluorinated crop-protection actives.

Fine chemical synthesis

Substrate for Friedel-Crafts, nitration and metalation chemistry.

Packaging & logistics

Packed to your site, documented for customs

2,4-Dichloro Fluoro Benzene is handled as a dangerous good. Every shipment leaves with UN-approved packaging, CLP labelling and the full document set for European import.

Drums

200 litre drums

UN-approved drums for FCL and LCL shipments. Net weight depends on density.

200 L nominal
IBCs

1,000 litre IBC totes

Intermediate bulk containers on pallets for bulk-liquid receiving.

1,000 L nominal
ISO tanks

ISO tank containers

For high-volume contract buyers with unloading infrastructure.

Bulk liquid
Document set included: Bill of lading · Commercial invoice · Packing list · Certificate of analysis (COA) · Safety data sheet (SDS) · Dangerous goods declaration (IMDG/ADR) · Certificate of origin · Other certificates on request
Common questions

2,4-Dichloro Fluoro Benzene: frequently asked questions

Quick answers for European buyers. For anything else, email source@cheloragroup.com.

It is also sold as 2,4-Dichlorofluorobenzene, 1,3-Dichloro-4-fluorobenzene, 2,4-DCFB. All refer to CAS 1435-48-9. Confirm the CAS number with any supplier before ordering.

Price depends on grade, volume, packing, Incoterm and destination port, and moves with raw material markets. Send us your requirement and we will quote in EUR or USD with a landed-cost breakdown, usually within one business day.

2,4-Dichloro Fluoro Benzene is a chloro-fluoro aromatic best known as the starting material for 2,4-dichloro-5-fluoroacetophenone, a central intermediate in fluoroquinolone antibiotic manufacture.

Standard grade offers 99.0% minimum GC purity. Premium grade offers 99.5% minimum, lower water content and inert-gas blanketed packaging. Premium is recommended for multi-step routes with tight impurity control.

Friedel-Crafts acylation places an acetyl group at the 5-position, giving an acetophenone that is built up into the quinolone core of several fluoroquinolone drugs.

Other dichlorofluorobenzene isomers and trichlorobenzenes. Ask for an isomer profile and set individual limits in your specification.

Store in closed containers in a cool, dry, ventilated place away from strong oxidisers and reactive metals. Use within the shelf life stated on the COA and TDS.

It is treated as a dangerous good (class and UN number per SDS; always confirm on the current SDS). We pack it in UN-approved containers, apply CLP labels and ship through licensed forwarders under IMDG for sea and ADR for European road.

Yes. Laboratory and pilot samples are supplied with a COA and SDS so your team can qualify the grade. Mention sample needs in your enquiry.

REACH status is confirmed before we quote. We advise on importer-of-record arrangements and whether the substance is registered for your use. Send your use descriptor and we will confirm.

Ready to source?

Get your 2,4-Dichloro Fluoro Benzene quotation today

Send us the grade, volume, destination and Incoterm. You will receive a clear price, packaging options and a full document checklist, usually within one business day.

  • Samples to full containers
  • COA, SDS and DG documents included as standard
  • Quote in EUR or USD, your choice of Incoterm